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None of these pathways directly substitute for another, which is part of why researchers interested in a fuller picture of metabolic regulation may look at all three within the same body of literature not to combine effects, but to understand how separate systems might interact at a mechanistic level

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ABC ATP-binding cassette, ECF electron-coupled factor, NiCoT nickel/cobalt transporter, MFS major facilitator factor, RND resistance nodulation division

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Because the IOMs RDA is considerably lower than the EFSAs AI, we chose to provide a lower recommendation to meet the RDA and a higher recommendation to meet the EFSAs AI