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Description
Metabotropic Glutamate Receptors (mGluRs) mGluRs, particularly mGluR1 and mGluR5, are G-protein-coupled receptors that modulate excitatory neurotransmission, synaptic plasticity, and intracellular signaling cascades through activation of phospholipase C (PLC) and the resulting production of inositol trisphosphate (IP 3 ) and diacylglycerol (DAG), ultimately leading to calcium release from intracellular stores and activation of protein kinase C (PKC)
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When compounds were detected in both ion modes, the one with the highest signal-to-noise ratio was retained
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Brain cells, including neurons, microglia, and astrocytes, also adhere to circadian rhythms [168,169,170]
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