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While some formulations may be stable at room temperature, it's best to refrigerate after opening to extend its shelf life

Tau is a cytoskeletal protein that stabilizes microtubules in neurons, but it is hyperphosphorylated in AD 66

Notch1 signaling plays a role in regulating precursor differentiation during CNS remyelination

[DOI] [PMC free article] [PubMed] [16].Wang Y, Chen X, Fan W, Zhang X, Zhan S, Zhong T, et al

However, in some cases, a VLCKD can increase inflammation [1, 32]
For more information and a detailed explanation of the GPCIs, see page 560 of the final rule