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5 The rule requires the submission of baseline or demographic characteristic measured in the clinical trial, including age, sex/gender, race, ethnicity (if collected under the protocol) for trials that are required to be registered under Section 11.22 (Phase 1 trials are excluded), 6 for reporting purposes via ClinicalTrials.gov

[22] [23] For example, motexafin gadolinium (MGd) is a new chemotherapeutic agent that selectively targets tumor cells, leading to cell death and apoptosis via inhibition of thioredoxin reductase and ribonucleotide reductase

doi: 10.3760/cma.j.cn121430-20220809-00731 107 WuTJWangSHChenESTsaiHHChangYCTsengYHet al

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Preliminary in vitro antisickilng properties of crude juice extracts of Persia Americana , citrus sinensis, Carica papaya and Ciklavit

These treatments include mB12/LDFA, BH4 and HDFA