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UV radiation is highly genotoxic but is also known as a significant prooxidant factor, which induces reactive oxygen species (ROS) generation by affecting cellular components directly or by means of photosensitization mechanisms 7 (Table 1)

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Over a period of 21 days, the zebrafish received treatment with AST at concentrations of 10 and 20 mg/L, along with donepezil at 1 mg/L and the MMP-13 inhibitor CL-82198 at 10 M

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