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Vallat-Decouvelaere AV, Wassef M, Lot G, Catala M, Moussalam M, Caruel N, Mikol J

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Non-visual effects of light on melatonin, alertness and cognitive performance: can blue-enriched light keep us alert

Notably, ncr-1(0) mutants displayed an impaired increase in the number of synapses in high cholesterol (Fig 1K and L), suggesting that NCR-1mediated cholesterol absorption is required for the formation of more synapses under high-cholesterol conditions

In the brain, choline is a precursor of various metabolites, including the neurotransmitter acetylcholine, membrane phospholipids (i.e., phosphatidylcholine and sphingomyelin) and the methyl donor betaine (Figure 1