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SIBO-MMC supports the MMC's primary serotonergic activation pathway via 5-HTP 98% 75mg (the direct serotonin precursor) + P-5-P active B6 15mg (its essential cofactor), combined with Ginger 5% gingerols 200mg (a clinically validated prokinetic that activates motilin and 5-HT4 receptors) and Jujube 2% jujuboside 200mg (enteric nervous system regulatory support).*

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Here, the authors show that early-life high-fat/high-sugar diet induces sex-specific alterations in adult feeding behavior, hypothalamic transcriptome and blood metabolome, with Bifidobacterium longum and prebiotic FOS+GOS administration restoring these effects via distinct mechanisms, highlighting their therapeutic potential.