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& McDonald, J
It is studied in research models for NNMT enzyme inhibition and downstream effects on cellular NAD+ and SAM metabolism

Given the permanent bidirectional communication between the brain and the other parts of the body in interoceptive networks, it would not be realistic to aim at fully disentangling the central and peripheral components of fatigue

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Xu YL, Wang DB, Liu QF, et al

*CPIC Guideline for CYP2D6 genotype and tamoxifen therapy
