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psychiatry 74, 708709

Fecal ezetimibe glucuronide excretion was significantly decreased whereas renal glucuronide excretion was increased in carriers of *1b/*1b

10.1186/s40164-023-00410-5 499 YinJ.LiaoS.-X.HeY.WangS.XiaG.-H.LiuF.-T.et al

Studies demonstrate that fibrotic microenvironments substantially compromise transplanted stem cell survival, with quantitative analyses showing a rapid decline in pulmonary tissue homing efficiency within 72 hours post-transplantation, ultimately limiting therapeutic outcomes ( Therefore, developing integrated strategies that combine standardized manufacturing of potent cell products with innovative bioengineering for targeted delivery and microenvironmental priming represents a pivotal research priority for regenerative medicine in pulmonary fibrosis ( 6.2 Safety concerns The principal barrier to clinical implementation of stem cell therapies lies in persistent safety considerations, including teratoma formation from residual undifferentiated cells, host immune responses, and uncontrolled differentiation

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Overall, the effectiveness of probiotic strains may depend not on their ability to colonize the gastrointestinal tract but rather on their ability to affect gene expression and metabolite levels and directly influence the intestinal barrier and immune cells