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Paclitaxel and camptothecin Paclitaxel (PTX) has been approved by the Food and Drug Administration as a radiation sensitizing drug

10.3390/ijms22062989 7 EzikeT

doi: 10.1186/s12909-024-05917-x 229 LiXYiMSongZNiTTuLYuMet al

The role of S1PR2 appears highly context-dependent, potentially exerting opposing effects in different tissues or disease states ( In summary, S1PR2 adds another layer of complexity to BA signaling within the TIME, potentially acting as a receptor for conjugated BAs to influence cancer cell invasiveness and inflammation, possibly contributing to a pro-tumorigenic microenvironment in certain settings

The dose-response curve for senolytic efficacy plateaus above 10mg/kg

Planta 133, 2125 10.1007/BF00386001 [DOI] [PubMed] [Google Scholar] 79.Chakravarthi S., Jessop C.E