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PXR then forms a complex with the retinoid X receptor (RXR), binds to DNA upstream of target genes, recruits coactivator (which binds to the TATA box binding protein, TBP), and activates transcription by RNA polymerase II (RNAP II)

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[DOI] [PMC free article] [PubMed] [Google Scholar] 22.Arajo-Rodrigues H., Amorim M., Sousa C., Salsinha A.S., Maral S., de Freitas V., Relvas J.B., Tavaria F.K., Pintado M.E

[DOI] [PubMed] [Google Scholar] 49.Moreau R, Valla DC, Durand-Zaleski I, Bronowicki JP, Durand F, Chaput JC, Dadamessi I, Silvain C, Bonny C, Oberti F, et al