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GBA-related PD (GBA-PD) is associated with faster motor and cognitive decline, especially affecting visuospatial and executive functions (De Michele et al., 2023), the rs12411216 variant of GBA being associated with PD-MCI (Jiang et al., 2020)

Bertolotti, M., Farinelli, G., Galli, M., Aiuti, A

In addition, consistent supplementation encourages long term improvement rather than short term change

Strategies intervening in this metabolic switch, inhibiting glycolysis and glutaminolysis, and promoting OXPHOSkeeping mitochondria healthycould be interesting strategies in the fight against these conditions and others related to the Warburg effect (Manzi et al., 2015

Apoptosis 19, 10991112

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