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The cytotoxicity assay results revealed that APE did not exhibit significant cytotoxic effects on RAW264.7 cells at concentrations up to 2000 g/mL

Individuals in a population can be stratified according to metabolic ratios of particular CYPs

Erickson HK, Lewis Phillips GD, Leipold DD, Provenzano CA, Mai E, Johnson HA, Gunter B, Audette CA, Gupta M, Pinkas J, Tibbitts J (2012) The effect of different linkers on target cell catabolism and pharmacokinetics/pharmacodynamics of trastuzumab maytansinoid conjugates

monocytogenes infection 4-HNE is a highly reactive electrophilic -unsaturated aldehyde that undergoes Michael addition with nucleophilic amino acids, resulting in stable conjugates that correlate with cellular levels of free 4-HNE

[DOI] [PMC free article] [PubMed] [Google Scholar] 105.Sawa T., Ono K., Tsutsuki H., Zhang T., Ida T., Nishida M., Akaike T

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