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GPX4 has been reported to be overexpressed in cancer tissues compared to normal tissues and to be associated with low levels of DNA methylation and enrichment of H3K4me3 and H3K27ac marks at its promoter, suggesting that epigenetic regulation may be involved in its aberrant overexpression[22]

Nanomechanotransduction and interphase nuclear organization influence on genomic control

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doi: 10.1074/jbc.C300368200 54 WolfG

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To determine the direct effect of GABA on WBPH, 20 insects were subjected to GABA (5, 10, or 15 mM) on plates after two hours of starvation ( Figure 3A )