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Iron overload enhances glycolysissupporting the M1 phenotype-and increases ROS production and p53 acetylation, further driving M1 polarization
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During ICD, DAMPs and pathogen-associated molecular patterns bind to pattern recognition receptors, generating anti-tumor immune responses
Both genetic and environmental factors have been found to play a significant role in the onset and progression of PD, with mutations in genes such as SNCA , which encodes -Syn, as one of the paradigmatic examples
Lactate-induced MRP1 expression contributes to metabolism-based etoposide resistance in non-small cell lung cancer cells
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