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Mitochondrial dysfunction elicits elevated ROS levels, which in turn promotes lipid hydroperoxide accumulation, potentially spreading beyond the mitochondrial compartment (109, 110)

Glutamine is catabolized by different enzymes, including GLS, CAD, or glutamine fructose 6 phosphate aminotransferase (GFAT)

Free Radicals and Antioxidants in Normal Physiological Functions and Human Disease
This work used the Integrated Structural Biology platform of the Strasbourg Instruct-ERIC center IGBMC-CBI supported by FRISBI (ANR-10-INBS-0005)

Implementing the aforementioned approaches may remain a formidable task due to constraints in both time and computational capacity

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