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supplementing with high doses of MeCbl may work well in many individuals, and it is the most cost-effective, naturally occurring form of supplemental B 12

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Pyridoxine (Vitamin B6) Vitamin B6 is a coenzyme for more than 100 enzyme reactions, including amino acid metabolism and neurotransmitter synthesis
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NNMT is a cytosolic enzyme that methylates nicotinamide (vitamin B3) using S-adenosylmethionine (SAM) as a methyl donor
