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Separately, work on peripheral nerve injury found BPC-157 accelerated functional recovery after traumatic nerve crush in rat models, pointing to a fourth application beyond soft tissue by Gjurasin 2010

These findings clearly show that BPC 157 may successfully compete with the initial events in intra-abdominal hypertension (i.e., significant damage to the intestinal epithelium and dilation of intestinal tight junctions, increased mucosal barrier permeability, bacterial translocation, and sepsis (Gong et al., 2009))

Evidence Boundary Included here only to clarify the evidence gap

Side Effects: What Is Reported and What Is Theoretical Because there is no large pharmacovigilance database for BPC-157, the current side-effect picture combines observations from the small human studies, clinician experience in regenerative medicine contexts, and self-report data from research communities

Astrogliosis during acute and chronic cuprizone demyelination and implications for remyelination

NSAIDS These drugs are sometimes used to relieve the pain and fever associated with ME/CFS