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The American Academy of Family Physicians and NIH identify the following clinical manifestations: Fatigue and generalized weakness Megaloblastic anemia (abnormally large, immature red blood cells) Tingling or numbness in the hands and feet (peripheral neuropathy) Difficulty walking and balance problems Cognitive disturbances including memory difficulty and confusion Mood changes, including depression and irritability Glossitis (swollen, inflamed tongue) Early symptoms such as fatigue and mild tingling are often attributed to stress, aging, or other conditions

10.3389/fcell.2019.00262 25 NavarreteF

Prevents hair shedding: Iron deficiency (anemia) is a leading cause of hair loss, as insufficient oxygen delivery weakens the follicles and disrupts the hair growth cycle

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