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It also contributes to the health of the skin and hair

The Imerslund-Grasbeck syndrome is a rare autosomal recessive condition characterized by both a specific congenital deficiency in cobalamin absorption and proteinuria (248)

The extraction and purification of vitamin B12 proceed through solvent extraction, chromatography and crystallization methods until pharmaceutical-grade purity is achieved

These include allergic reactions, which can be very serious