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For athletes and sport-competing individuals, a separate concern applies: BPC-157 is prohibited under the World Anti-Doping Agency's S0 category of non-approved substances, which covers any pharmacological agent not approved for human therapeutic use by any regulatory body

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Ipamorelin, a selective ghrelin receptor agonist, promotes GH release by inhibiting somatostatin and is noted for its minimal off-target endocrine effects, particularly on cortisol and prolactin

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The practice is legal but generates significant antitrust scrutiny when the patents are weak