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Specifically, while adult KI mice exhibited robust anxiety-like behaviors within the first 48 h following SDS, these effects were largely attenuated one week later, with only limited and parameter-specific alterations remaining

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Nearly all of the identified causal genes for Mendelian forms of human blood pressure abnormalities involve kidney function 7,8 , and most of the commonly used animal models of hypertension present kidney abnormalities 9

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