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Biomaterials 316:123024 Wu KK, Xu X, Wu M, Li X, Hoque M, Li GHY, Lian Q, Long K, Zhou T, Piao H, Xu A, Hui HX, Cheng KK (2024) MDM2 induces pro-inflammatory and glycolytic responses in M1 macrophages by integrating iNOS-nitric oxide and HIF-1 pathways in mice

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Physiological ovarian aging (NOA) is the gradual loss of ovarian reserve function in older women until they reach menopause while pathological ovarian aging is the premature ovarian failure caused by various pathogenic factors, including decreased ovarian reserve (DOR), ovarian insufficiency (POI) and poor ovarian response (POR) ( in vivo , and in vitro research