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Interestingly, Parkin-deficient mice demonstrated a reduction of several subunits of complexes I and IV, decreased mitochondrial respiratory capacity in the striatum, and lower levels of proteins involved in protection against oxidative stress [96]

JohnsonLQuinnGEAbbasiSOtisCGoldsteinDSacksLet al

This compound not only inhibited SARM1s NADase activity effectively but also exhibited a favorable safety profile, making it a strong candidate for further development 233

The transcript of the Trx-coding MAL13P1.225 is already high immediately following invasion (Fig

The increase of neuron-specific enolase in cerebrospinal fluid and plasma as a marker of neuronal damage in patients with acute brain infarction

Bibcode:2002IJMSp.221..117D