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256 However, when the kidney undergoes damage, Wnt/-catenin and Wnt/Ca 2+ signaling is promoted, which further damages the kidney via cell senescence, renal fibrosis, oxidative stress, apoptosis, and ferroptosis pathways, thereby causing AKI or chronic kidney disease (CKD)

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Consumption of hydrogen water reduced levels of TNF-, IL-6, IL-1, chemokine (C-C motif) ligand 2, and other inflammation markers in multiple rodent models through inhibition of pathways like NF-kB and JNK [26]

While occasional constipation is normal, frequent constipation can be a sign of an underlying health condition

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