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G6PD-deficient cells are unable to generate enough NADPH under the condition of severe thiol depletion and GSH biosynthesis and methionine cycle are upregulated at the expense of ATP but fail to compensate for GSH depletion (311)

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117010 (Environmental Health Perspectives, 2023)

Unlike most antioxidants that we obtain from our diet, glutathione is unique because our body can produce it naturally