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In this model, iodine deficiency and Se deficiency exacerbate H2O2 accumulation, Se deficiency decreases cellular defense, promotes thyroid cell fibrosis, increases the inflammatory response following thyroid cell necrosis, and thiocyanate overload triggers follicular cell necrosis
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The CPT system is an important component of the carnitine shuttle which facilitates the transport of long-chain fatty acids from cytosol into the mitochondrial matrix, the site of -oxidation (Figure 2)
Neurotrophic factors are associated with the pathogenesis of depression (87, 88)
Neurochem Res 35:743748 Reuter SE, Evans AM (2012) Carnitine and acylcarnitines: pharmacokinetic, pharmacological and clinical aspects
