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The GLP-1R, present in glutamatergic neurons in hypothalamic nuclei such as the arcuate nucleus and the paraventricular nucleus (PVN), contributes to the increased hepatic FGF21 most likely via direct autonomic nervous system circuits from the brain to the liver
CPT-I is located on the outer mitochondrial membrane and is the rate-limiting enzyme for fatty acid transport
Agarwal A, Gupta S, Sikka S
96: 235660 Wu X, Huang W, Prasad PD, et al
