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Worldwide there is not only a shortage of funding for available treatments, but a severe shortage of personnel trained to diagnose the condition and manage it appropriately (259)

Data Availability Statement All clinical recommendations made in the review article are based on published clinical trials, research, clinical experience and case reports, and are well referenced.

1 Introduction Heart failure (HF) is one of the most prevalent cardiovascular diseases worldwide and poses a significant threat to human health (Zannad, 2018)

[DOI] [PMC free article] [PubMed] [Google Scholar] 94.Haschemi A et al

Like any procedure involving the blood, it carries risks that depend on technique, equipment, and your individual health, which is why screening and supervision matter

FOXO forkhead transcription factors induce G2-M checkpoint in response to oxidative stress