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The CNS also receives and processes internal and external stimuli prior to signaling through the peripheral nervous system (PNS) to the white, brown, and beige adipose tissues to control metabolic activities such as lipolysis, thermogenesis, and beiging through efferent pathways (569)

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doi: 10.1177/156482650402500203

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Thus, we aimed to conduct this systematic review to appraise the current evidence for ALC use in the treatment of depression in mood disorders