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doi: 10.1074/jbc.M805770200

Subsequently, homotypic targeting of tumor cell membranes has been verified in various cancer treatments, including breast cancer MCF-7 cells [57], 4T1 cells [58], osteosarcoma HOS cells [59], bladder cancer T24 cells [60], and colon cancer CT26 cells [58]

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Since AUC sedimentation velocity (SV-AUC, where the rotor is spun at sufficiently high speed to allow measurement of the rate at which macromolecules move through a solution under high centrifugal force) and sedimentation equilibrium (SE-AUC, where the rotor speed is lower permitting to reach a state of equilibrium, where the centrifugal force driving sedimentation is balanced by diffusion) provide crucial information about the macromolecular properties, such as molecular weight, sedimentation, diffusion, frictional coefficients, shape, and formation of protein complexes, this technique rapidly became a major tool for the analysis of polymers, colloids, and proteins (Clfen, 2023)

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