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if skin is sensitive, start using 23 times per week and, if tolerated, increase to daily use

10.3390/ijms241310574 Int J Mol Sci

Unlike synthetic hormone formulations, bioidentical hormones are designed to match the body's own chemistry

doi: 10.1097/00000542-199612000-00028
A notable difference between the two isoenzymes is the presence of NAT1 activity in fetal and neonatal tissue, such as lungs, kidneys, and adrenal glands (Pacifici et al., 1986)

doi: 10.1371/journal.pone.0021827 277 ToK.CaoR.YegiazaryanA.OwensJ.NguyenT.SasaniniaK.et al
