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Personalized neoantigen vaccines have shown efficacy in treating lung cancer [193, 194]

This process activates the colonic ferroptosis pathway and induces systemic inflammation (Gu et al., 2023)

Botella JA, Bayersdorfer F, Schneuwly S

[DOI] [PMC free article] [PubMed] [Google Scholar] 141.Hira S., Saleem U., Anwar F., Sohail M.F., Raza Z., Ahmad B

Alterations in insulin signaling, a hallmark in adults with type 2 diabetes mellitus (T2DM), have also been observed in individuals with PD

For instance, the PTEN protein and cytosolic TP53 bind to G6PD to prevent the assembly of G6PD monomers into active dimers and thus decease the PPP flux