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Description
Our results show that glutathione efflux from hepatocytes results in high local concentrations of both glutathione and cysteine in liver sinusoids, which transforms the nanoparticle surface chemistry, reduces its affinity to serum protein and significantly alters its blood retention, targeting and clearance
The highest concentrations of FA were found in studies conducted in China, 32 Colombia 3 and Tunisia, 36 while the lowest concentrations, with values below permissible exposure limits, were found in a research conducted at a wood manufacturing center in Brazil
De Lange ECM, Vd Berg DJ, Bellanti F, Voskuyl RA, Syvanen S
doi: 10.1016/j.clinbiochem.2020.01.003 211 SchlegelVTreuner-KaueroffTSeehoferDBergTBeckerSCeglarekUet al
Funding DJ Fazakerley was supported by a Medical Research Council Career Development Award (MR/S007091/1)
S-nitrosylation of peroxiredoxin II E promotes peroxynitrite-mediated tyrosine nitration
