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10.1146/annurev-physiol-022516-034227 28 InkerL

GSH reduces disulfide bonds of GP-120, decreasing or eliminating its biological activity, which in turn is necessary for viral infectivity

2 measured reduced and oxidized hepatic GSH concentrations during alcoholic and nonalcoholic liver injury in 35 chronic alcoholics, 20 nonalcoholic patients with liver disease (chronic active hepatitis, chronic persisting hepatitis, steatosis, cirrhosis), and 15 control patients (admitted for uncomplicated abdominal procedures)

These adverse effects are generally mild to moderate and improve over time, but they are the most frequent reason for treatment discontinuation

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Microglia/astrocytes-glioblastoma crosstalk: crucial molecular mechanisms and microenvironmental factors