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The preclinical results are robust and the mechanistic rationale is strong, but caution is warranted until larger, controlled human trials are completed

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In the control groups, there was no change in GSH concentration with the different brew treatment (Fig

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Clin Pharmacol Ther 31:151156 Miners JO, Penhall R, Robson RA, Birkett DJ (1988) Comparison of paracetamol metabolism in young adult and elderly males