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Intestinal barrier dysfunction results from food poisoning, dietary factors, and dysbiosis, and increased permeability leads to the translocation of sterile toxins and living or dormant microbes and lipopolysaccharides (LPS) into the bloodstream (de Punder and Pruimboom, 2013

Elucidation of unknown reactions and structures We used the known metabolic reactions in the reference reaction library as references to deduce the structures of unknowns in the unknown metabolic reactions

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Guilloz in 1954