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In the RT structure, the cyano group at the position of the Michael acceptor enables fast reaction kinetics, the four-membered azetidine ring improves quantum yield and photostability 17 , and the two carboxylic acid groups ensure aqueous solubility and reduce probe binding to hydrophobic cellular structures

oryzae and rapid growth characteristics make this strain an attractive host for heterologous biosynthesis

10.1186/s12934-019-1229-3A [DOI] [PMC free article] [PubMed] [Google Scholar] Kumar, R

GBM cells exhibit dysregulated iron metabolism (transferrin receptor overexpression, impaired iron efflux) and altered lipid metabolism (changes in desaturase activity, membrane phospholipid remodeling), conferring heightened ferroptosis susceptibility compared to normal neural cells [10]