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More importantly, the increasing of iron uptake caused by CD44 overexpression and the decreasing iron efflux caused by downregulating FPN in CSCs cause intracellular iron to be higher than non-CSCs
TRIM40 promotes neddylation of IKKgamma and is downregulated in gastrointestinal cancers
& Heiger, D
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Following the completion of the behavioural tests, the mice were humanely euthanized under deep anesthesia, which was induced by administering ketamine (60 mg/kg) and xylazine (10 mg/kg) intraperitoneally
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