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In rodents testis, PHGPx is localized in the interstitial cells of Leydig, in the nucleus of round spermatids, at the level of the cytoplasm and in the mitochondrial capsule of spermatozoa (25)

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doi: 10.1016/j.euf.2018.02.006 8 KouidratYPizzolDCoscoTThompsonTCarnaghiMBertoldoAet al

Human trial data is limited to a handful of small pilot studies, and a 2025 University of Utah review concludes BPC-157 should be considered investigational