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Polysaccharide peptides from Ganoderma lucidum ameliorate lipid metabolic disorders and gut microbiota dysbiosis in high-fat diet-fed rats

However, so far as I understand, even that only points at one specific aspect of kidney function - not more general impaired kidney function

Monti DA, Newberg AB, Forehand V, et al

Endogenous opioids and attenuated hypothalamic-pituitary-adrenal axis responses to immune challenge in pregnant rats

Rezamahaleh FA, Khadivzadeh T, Asgharinekah SM, Esmaeili H

Research suggests it may have systemic effects, including benefits for tissue repair, inflammation, and overall cellular health