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Furthermore, encouraging data from recent interventional studies favor the benefit of homocysteine-lowering therapy in the prevention and correction of vascular disorders related to elevated homocysteine levels

7.5 Critical discussion of translational challenges The translation of ferroptosis-targeting agents for AD faces multiple interconnected challenges, with BBB penetration, off-target effects, long-term safety, and perturbations of iron metabolism and immune function being the most prominent

Kuruvilla A, Shah R, Hochwald G, Liggitt H, Palladino M, Thorbecke G

Using elevated cholesterol synthesis as a prognostic marker in wilms Tumor: A bioinformatic analysis

Dihexas specific HGF/c-Met mechanism drives synaptogenesis at a structural level potentially creating lasting new neural connections rather than transient neurochemical changes

Van Heerden, F