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Phospholipid synthesis in a membrane fraction associated with mitochondria

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It facilitates glymphatic clearance, a convective exchange of CSF and interstitial fluid (ISF) that removes metabolic waste, but also A and tau [359, 366]

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This superoxide anion (O 2 ) can either spontaneously or enzymatically (via superoxide dismutase, SOD) dismutate into hydrogen peroxide (H 2 O 2 ) (Akagawa et al., 2016a)