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This review is focused on the use of poly (lactic-co-glycolic acid) (PLGA)-based nanosystem as advanced drug delivery carriers for PD due to its versatility, safety, biodegradability, and extensive studies which evaluated the use of PLGA for drug delivery

In addition to PARK6 (encoding PINK1) and PARK2 (encoding Parkin), other genes associated with Parkinsons disease, such as PARK7 (encoding the DJ-1 protein) and PARK8 (encoding the LRRK2 protein), are also thought to be mutated in patients with Parkinsons disease (Walter et al., 2019)

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