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This has profound downstream effects, including boosting cellular metabolism, promoting fat breakdown (lipolysis), and reducing the accumulation of adipose tissue in preclinical models

The National Sleep Foundation recommends that adults should aim for between 7-9 hours for optimum sleep a night, possibly falling to 7-8 hours for the over-65s

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The Framingham Offspring study found that 39% of the general population may be in the low normal + deficient B12 blood level range

While the condition is the major cause of poor vitamin B 12 status in the elderly population, it is usually associated with atrophic gastritis, a chronic inflammation of the lining of the stomach that ultimately results in the loss of glands in the stomach (atrophy) and decreased stomach acid production (see Atrophic gastritis)
