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Losartan is an angiotensin II receptor antagonist, competing with the binding of angiotensin II to AT1 receptors with IC50 of 20 nM

Impairment of fertility: In sub-chronic/chronic toxicity studies, testicular degeneration/atrophy or spermatogenesis abnormalities and a decrease in testes weight were reported in adult rats and dogs after oral administration starting at doses of 1250 mg/kg/day and 150 mg/kg/day, respectively

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Over-the-counter (OTC) and prescription drugs are two distinct categories of medications available to consumers, primarily differentiated by their accessibility and the level of regulatory control.Here's a comprehensive comparison:Over-the-Counter (OTC) Drugs: Accessibility:Can be purchased directly by consumers without a prescription from a healthcare professional.They are readily available in pharmacies, grocery stores, convenience stores, and even gas stations