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Keywords: Liver disease, Hormonal imbalance, Endocrine disorders, Cirrhosis, Liver dysfunction, Liver pathology, Metabolic liver disease Core Tip: This review highlights the intricate relationship between endocrine disorders and liver dysfunction, emphasizing the role of hormonal imbalances in the development and progression of liver disease

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CA was also significantly increased in the urine samples and the increase was noted prior to visible histological changes and increases in ALT

The compound reduces hematocrit and hemoglobin levels, probably by inducing oxidative stress in erythrocytes

However, free heme can be toxic as it catalyzes the production of reactive oxygen species, oxidizes lipids and proteins, and causes DNA damage, thereby inducing a pro-inflammatory environment