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The mTORC2 complex affects cell survival through signaling via the Akt pathway and cytoskeletal dynamics through interactions with PKC

Kuloglu M, Ustundag B, Atmaca M, Canatan H, Tezcan AE, Cinkilinc N

This distinction matters because it means existing contamination still poses a risk

These patients often display multisystem involvement, including hepatomegaly, hypoketotic hypoglycemia, elevated ammonia levels in blood, organic acidosis, and hepatic encephalopathy

doi: 10.1089/thy.2010.0244 17 BazzichiLRossiAGiulianoTDe FeoFGiacomelliCConsensiAet al

287 Multiple sclerosis Multiple sclerosis (MS) is a chronic autoimmune inflammatory disease with antibodies primarily attacking myelin sheaths and causing multiple demyelinated areas in white and grey matter throughout the CNS (with most frequent localisation in the optic nerve, spinal cord, brain stem, periventricular white matter, and the grey matter near the subarachnoid space)
