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[DOI] [PubMed] [Google Scholar] 101.Zhou Y., Tang J., Du Y., Ding J., Liu J.Y

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As 5-FU-based chemotherapy relies on active DNA replication to take effect, this quiescent non-replicating state prevents 5-FU from its intended activity

However, it is important to strike that although these data underscore the significance of GSH depletion for a short period of time (up to 24 hours), it is conceivable that depletion of GSH per se for serveral days may result in a different outcome

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