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While typically painless, the hypertrophied glands can occasionally cause discomfort or acute pain if salivary ducts become transiently obstructed or inflamed

doi: 10.1186/s40409-017-0106-y 6 DinizAGBelminoJFArajoKAVieiraATLeite RdeS

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Other mechanisms that could potentially explain ferric accumulation in PD are increased lactoferrin receptor in neurons and microvessels, increased DMT1 in DAergic neurons, and genetically-determined impaired in iron transport and binding (Mastroberardino et al., 2009

doi: 10.1172/JCI18309 244 ThywienAHeinekampTDahseHMSchmaler-RipckeJNietzscheSZipfelPFet al

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